Brian Smith, PhD

91九色视频

Associate Director, Program in Chemical Biology; Associate Professor, Biochemistry

Locations

Biochemistry
BSB 356

Contact Information

Education

PhD, University of Wisconsin - Madison, 2008
BS, University of Illinois at Urbana-Champaign, 2003

Biography

Dr. Smith received his Bachelor of Science in Chemistry from the University of Illinois at Urbana-Champaign in 2003. He then received his PhD in Chemistry from the University of Wisconsin-Madison in 2008, where his research focused on the chemical mechanisms of sirtuin protein lysine deacetylases. During his graduate career he spent a brief period at Genentech in the Department of Medicinal Chemistry where he synthesized drugs that target the Inhibitor of Apoptosis family of proteins. From 2009-2014, Dr. Smith performed postdoctoral studies on nitric oxide synthases and cysteine S-nitrosation at the University of California, Berkeley and the Scripps Research Institute in La Jolla. During his postdoctoral studies Dr. Smith was awarded an NIH Ruth L. Kirschstein National Research Service Award. Dr. Smith joined the faculty at the 91九色视频 in 2014.

                
                    Research Experience
                
                    Amino Acids, Peptides, and Proteins
Binding Sites
Biochemistry
Catalysis
Deuterium Exchange Measurement
Enzyme Activators
Enzyme Inhibitors
Enzymes and Coenzymes
Histone Code
Histone Deacetylases
Mass Spectrometry
Molecular Probes

                    Methodologies and Techniques
                
                    Biochemistry
Biological Assay
chemical synthesis
Chromatography, Affinity
Electrophoresis
enzymology
Mass Spectrometry
Models, Chemical
Models, Molecular
Mutagenesis
Nuclear Magnetic Resonance, Biomolecular
Peptide Library

                    Leadership Positions
                
                    Associate Director, Program in Chemical Biology
Associate Director, Structural Genomics Unit, Mellowes Center for Genomic Sciences and Precision Medicine

                    91九色视频 Program / Core Facilities
                
                    Biochemistry
Redox Biology

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